| http://purl.uniprot.org/citations/9772904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9772904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9772904 | http://www.w3.org/2000/01/rdf-schema#comment | "Parosteal lipomas are rare benign neoplasms of adipose tissue that exhibit a contiguous relationship with the periosteum. These lipomas of the bone share some histopathologic features with their commonly occurring soft tissue counterparts. The latter are well-characterized cytogenetically, primarily by rearrangements involving chromosome region 12q13-q15. In particular, translocations involving 12q13-q15 are prominent, with chromosomal region 3q27-q28 as the most frequent translocation partner. Recently, we established that the genes HMGIC at 12q15 and LPP at 3q27-28 are affected by the 3;12-translocation and demonstrated that, as a direct result, HMGIC/LPP and LPP/HMGIC fusion transcripts are expressed in soft tissue lipomas. In this study, cytogenetic and molecular analyses revealed similar findings in a parosteal lipoma. Specifically, a t(3;12)(q28;q14) was detected cytogenetically in a parosteal lipoma from a 51-year-old female and subsequently confirmed by FISH utilizing a chromosome 3 breakpoint spanning YAC probe and chromosome 12 breakpoint flanking cosmid probes. RT-PCR analysis showed expression of HMGIC/LPP and LPP/HMGIC fusion transcripts in this parosteal lipoma; nucleotide sequence analysis revealed that these transcripts are identical to those expressed in soft tissue lipomas characterized by a 3;12-translocation. These findings lend further support to a common histopathogenesis between lipomas of soft tissue and parosteal origin."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0165-4608(98)00038-7"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0165-4608(98)00038-7"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Bridge J.A."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Bridge J.A."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Van de Ven W.J.M."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Van de Ven W.J.M."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Petit M.M."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Petit M.M."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Swarts S."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/author | "Swarts S."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/name | "Cancer Genet. Cytogenet."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/name | "Cancer Genet. Cytogenet."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/pages | "18-23"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/pages | "18-23"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/title | "Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/title | "Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma."xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/9772904 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9772904 |
| http://purl.uniprot.org/citations/9772904 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9772904 |