http://purl.uniprot.org/citations/9774970 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9774970 | http://www.w3.org/2000/01/rdf-schema#comment | "BRCA1 and BRCA2 account for most cases of familial, early onset breast and/or ovarian cancer and encode products that each interact with hRAD51. Results presented here show that BRCA1 and BRCA2 coexist in a biochemical complex and colocalize in subnuclear foci in somatic cells and on the axial elements of developing synaptonemal complexes. Like BRCA1 and RAD51, BRCA2 relocates to PCNA+ replication sites following exposure of S phase cells to hydroxyurea or UV irradiation. Thus, BRCA1 and BRCA2 participate, together, in a pathway(s) associated with the activation of double-strand break repair and/or homologous recombination. Dysfunction of this pathway may be a general phenomenon in the majority of cases of hereditary breast and/or ovarian cancer."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80276-2"xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Chen J."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Gazdar A.F."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Weber B.L."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Livingston D.M."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Scully R."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Couch F.J."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Ashley T."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Cantor S.B."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Tomlinson G."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Silver D.P."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/author | "Walpita D."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/pages | "317-328"xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/title | "Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells."xsd:string |
http://purl.uniprot.org/citations/9774970 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/9774970 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9774970 |
http://purl.uniprot.org/citations/9774970 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9774970 |
http://purl.uniprot.org/uniprot/P38398#attribution-3CC5820F1D065C374F2F895F46D0CFB3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9774970 |
http://purl.uniprot.org/uniprot/P38398#attribution-D594368640A369C029C05BD2F398F22C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9774970 |
http://purl.uniprot.org/uniprot/P48754#attribution-6D92F0AE2B6D36C634428E50A31514E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9774970 |
http://purl.uniprot.org/uniprot/P51587#attribution-3CC5820F1D065C374F2F895F46D0CFB3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9774970 |