http://purl.uniprot.org/citations/9780260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9780260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9780260 | http://www.w3.org/2000/01/rdf-schema#comment | "Some clinical isolates of Helicobacter pylori fail to express vacuolating cytotoxin, despite possessing a copy of the vacA gene on the chromosome. To gain insight into the differences between vacA from cytotoxic and noncytotoxic strains, the vacA open-reading frames from 16 cytotoxic and 22 noncytotoxic strains were sequenced. Mutations that cause truncation of VacA in 11 of 22 noncytotoxic strains were identified, including internal duplication, large deletion, 1-bp insertion, and non-sense mutations. In contrast, none of the 16 cytotoxic strains had any truncation of VacA. Four cytotoxic strains had inserted sequences downstream of vacA. Three were mini-IS605, and the other was a putative rfaJ gene that encodes lipopolysaccharide glucosyltransferase. The rfaJ gene identified in this study had a poly(C) tract, resulting in premature termination of the gene product. The phylogenetic tree based on the vacA open-reading frame indicated that two different H. pylori lineages are circulating in Japan and the West."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.org/dc/terms/identifier | "doi:10.1086/314435"xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.org/dc/terms/identifier | "doi:10.1086/314435"xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Ito S."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Ito S."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Ito Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Ito Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Yamazaki Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Yamazaki Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Azuma T."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Azuma T."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Kuriyama M."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Kuriyama M."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Suto H."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Suto H."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Kohli Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Kohli Y."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Miyaji H."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/author | "Miyaji H."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/name | "J. Infect. Dis."xsd:string |
http://purl.uniprot.org/citations/9780260 | http://purl.uniprot.org/core/name | "J Infect Dis"xsd:string |