http://purl.uniprot.org/citations/9780336 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9780336 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9780336 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we report the isolation and characterization of mouse testicular cDNAs encoding the mammalian homologue of the Xenopus germ cell-specific nucleic acid-binding protein FRGY2 (mRNP3+4), hereafter designated MSY2. MSY2 is a member of the Y box multigene family of proteins; it contains the cold shock domain that is highly conserved among all Y box proteins and four basic/aromatic islands that are closely related to the other known germline Y box proteins from Xenopus, FRGY2, and goldfish, GFYP2. Msy2 undergoes alternative splicing to yield alternate N-terminal regions upstream of the cold shock domain. Although MSY2 is a member of a large family of nucleic acid-binding proteins, Southern blotting detects only a limited number of genomic DNA fragments, suggesting that Msy2 is a single copy gene. By Northern blotting and immunoblotting, MSY2 appears to be a germ cell-specific protein in the testis. Analysis of Msy2 mRNA expression in prepubertal and adult mouse testes, and in isolated populations of germ cells, reveals maximal expression in postmeiotic round spermatids, a cell type with abundant amounts of stored messenger ribonucleoproteins. In the ovary, MSY2 is present exclusively in diplotene-stage and mature oocytes. MSY2 is maternally inherited in the one-cell-stage embryo but is not detected in the late two-cell-stage embryo. This loss of MSY2 is coincident with the bulk degradation of maternal mRNAs in the two-cell embryo."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.org/dc/terms/identifier | "doi:10.1095/biolreprod59.5.1266"xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.org/dc/terms/identifier | "doi:10.1095/biolreprod59.5.1266"xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Gu W."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Gu W."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Hecht N.B."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Hecht N.B."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Eppig J.J."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Eppig J.J."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Reinbold R."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Reinbold R."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Choi Y.-C."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Choi Y.-C."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Murray M.T."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Murray M.T."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Zheng J.Z."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Zheng J.Z."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Tekur S."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/author | "Tekur S."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/name | "Biol. Reprod."xsd:string |
http://purl.uniprot.org/citations/9780336 | http://purl.uniprot.org/core/name | "Biol. Reprod."xsd:string |