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http://purl.uniprot.org/citations/9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9787642http://www.w3.org/2000/01/rdf-schema#comment"Intercellular signaling through the Notch/LIN-12 transmembrane receptors regulates growth and differentiation during animal development. Moreover, defects in the conserved Notch/LIN-12 pathway are linked to human diseases. Here, we review models for two key steps in Notch/LIN-12 signaling: ligand-mediated activation of the receptor and receptor-mediated activation of transcription. Ligand binding appears to permit proteolysis of the receptor; as a result, the receptor's intracellular domain can enter the nucleus and function as a transcriptional co-activator."xsd:string
http://purl.uniprot.org/citations/9787642http://purl.org/dc/terms/identifier"doi:10.1016/s0968-0004(98)01263-8"xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/author"Kimble J."xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/author"Henderson S."xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/author"Crittenden S."xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/name"Trends Biochem Sci"xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/pages"353-357"xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/title"Notch/LIN-12 signaling: transduction by regulated protein slicing."xsd:string
http://purl.uniprot.org/citations/9787642http://purl.uniprot.org/core/volume"23"xsd:string
http://purl.uniprot.org/citations/9787642http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9787642
http://purl.uniprot.org/citations/9787642http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9787642
http://purl.uniprot.org/uniprot/#_A0A0B4LIS1-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_A8DZ02-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_A8DZ03-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_A4V346-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_P10041-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_P28159-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_M9NE67-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_Q7YSQ1-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_Q7YSR5-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_Q7YSU6-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_Q7Z1J3-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642
http://purl.uniprot.org/uniprot/#_P07207-mappedCitation-9787642http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9787642