| http://purl.uniprot.org/citations/9790534 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9790534 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9790534 | http://www.w3.org/2000/01/rdf-schema#comment | "Histone acetylation and deacetylation were found to be catalyzed by structurally distinct, multisubunit complexes that mediate, respectively, activation and repression of transcription. ATP-dependent nucleosome remodeling, mediated by different multisubunit complexes, was thought to be involved only in transcription activation. Here we report the isolation of a protein complex that contains both histone deacetylation and ATP-dependent nucleosome remodeling activities. The complex contains the histone deacetylases HDAC1/2, histone-binding proteins, the dermatomyositis-specific autoantigen Mi2beta, a polypeptide related to the metastasis-associated protein 1, and a novel polypeptide of 32 kDa. Patients with dermatomyositis have a high rate of malignancy. The finding that Mi2beta exists in a complex containing histone deacetylase and nucleosome remodeling activities suggests a role for chromatin reorganization in cancer metastasis."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81758-4"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81758-4"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Lane W.S."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Lane W.S."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Reinberg D."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Reinberg D."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "LeRoy G."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "LeRoy G."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Seelig H.-P."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/author | "Seelig H.-P."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/pages | "279-289"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/pages | "279-289"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/title | "The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/title | "The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities."xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/volume | "95"xsd:string |
| http://purl.uniprot.org/citations/9790534 | http://purl.uniprot.org/core/volume | "95"xsd:string |