| http://purl.uniprot.org/citations/9809553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9809553 | http://www.w3.org/2000/01/rdf-schema#comment | "Fas ligand is a well-characterized apoptosis inducer. Here we demonstrate that Fas ligand induces the processing and secretion of interleukin-1beta (IL-1beta) in peritoneal exudate cells. This IL-1beta secretion is independent of IL-1beta converting enzyme (caspase 1), yet it is inhibited by caspase inhibitors, indicating that a caspase(s) in addition to IL-1beta converting enzyme can process IL-1beta. Inoculation of tumor cells expressing Fas ligand into wild-type mice induces a massive neutrophil infiltration that is, in contrast, suppressed in IL-1alpha/beta knockout mice. These results demonstrate a newly discovered role for Fas ligand in inflammation, and challenge the dogma that apoptosis does not induce inflammation."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.org/dc/terms/identifier | "doi:10.1038/3276"xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Asano M."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Suda T."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Miwa K."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Nagata S."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Iwakura Y."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/author | "Horai R."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/name | "Nat Med"xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/pages | "1287-1292"xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/title | "Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand."xsd:string |
| http://purl.uniprot.org/citations/9809553 | http://purl.uniprot.org/core/volume | "4"xsd:string |
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