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http://purl.uniprot.org/citations/9813377 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice lacking surfactant protein A (SP-A) mRNA and protein in vivo were generated using gene targeting techniques. SP-A (-/-) mice have normal levels of SP-B, SP-C and SP-D mRNA and protein and survive and breed normally in vivarium conditions. Phospholipid composition, secretion and clearance, and incorporation of phospholipid precursors are normal in the SP-A (-/-) mice. Lungs of SP-A (-/-) mice have markedly decreased tubular myelin figures and clear Group B streptococci and Pseudomonas aeruginosa less efficiently than SP-A wild type mice. These studies of SP-A (-/-) mice demonstrate that SP-A has an important role in the innate immune system of the lung in vivo."xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0925-4439(98)00075-1"xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/author | "Whitsett J.A."xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/author | "Korfhagen T.R."xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/author | "LeVine A.M."xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/pages | "296-302"xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/title | "Surfactant protein A (SP-A) gene targeted mice."xsd:string |
http://purl.uniprot.org/citations/9813377 | http://purl.uniprot.org/core/volume | "1408"xsd:string |
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