| http://purl.uniprot.org/citations/9822591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9822591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9822591 | http://www.w3.org/2000/01/rdf-schema#comment | "Two membrane proteins were identified through their genetic interaction with the nucleoporin Nup84p and shown to participate in nuclear envelope morphogenesis in yeast. One component is a known sporulation factor Spo7p, and the other, Nem1p, a novel protein whose C-terminal domain is conserved during eukaryotic evolution. Spo7p and Nem1p localize to the nuclear/ER membrane and behave biochemically as integral membrane proteins. Nem1p binds to Spo7p via its conserved C-terminal domain. Although cells without Spo7p or Nem1p are viable, they exhibit a drastically altered nuclear morphology with long, pore-containing double nuclear membrane extensions. These protrusions emanate from a core nucleus which contains the DNA, and penetrate deeply into the cytoplasm. Interestingly, not only Spo7(-) and Nem1(-), but also several nucleoporin mutants are defective in sporulation. Thus, Spo7p and Nem1p, which exhibit a strong genetic link to nucleoporins of the Nup84p complex, fulfil an essential role in formation of a spherical nucleus and meiotic division."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/17.22.6449"xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/17.22.6449"xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Mann M."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Mann M."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Rappsilber J."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Rappsilber J."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Hurt E."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Hurt E."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Siniossoglou S."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Siniossoglou S."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Santos-Rosa H."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/author | "Santos-Rosa H."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/pages | "6449-6464"xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/pages | "6449-6464"xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/title | "A novel complex of membrane proteins required for formation of a spherical nucleus."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/title | "A novel complex of membrane proteins required for formation of a spherical nucleus."xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/9822591 | http://purl.uniprot.org/core/volume | "17"xsd:string |