| http://purl.uniprot.org/citations/9832052 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9832052 | http://www.w3.org/2000/01/rdf-schema#comment | "Interstitial cells of Cajal (ICC) are believed to initiate the basic contractile activity of the gastrointestinal tract. Interstitial cells of Cajal express c-kit receptor tyrosine kinase and are deficient in Ws/Ws mutant rats with a small deletion of the c-kit gene. As Ws/Ws rats show remarkable bile reflux to the stomach, the contraction pressure of the pylorus was compared between Ws/Ws and control +/+ rats. The contraction pressure of the pylorus was measured using a microtransducer, which was inserted through a pin-hole in the anterior wall of the stomach under anesthesia. The magnitude of bile reflux was estimated by measuring the content of bile acids in the stomach. The c-kit messenger RNA-expressing cells were detected by in situ hybridization. Frequency and the maximum pressure of the contraction were comparable between Ws/Ws and +/+ rats, but the duration of the contraction was significantly shorter in Ws/Ws rats than in +/+ rats. The number of c-kit messenger RNA-expressing ICC in the pylorus of Ws/Ws rats was 1.7% that of +/+ rats. The bile reflux observed in Ws/Ws rats was attributed to the decrease in the duration of the pyloric contraction, which appeared to result from the deficiency of c-kit messenger RNA-expressing ICC."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1440-1827.1998.tb03850.x"xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Okazaki T."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Kawano S."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Kitamura Y."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Nagano K."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Hori M."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Hirota S."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/author | "Nakama A."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/name | "Pathol Int"xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/pages | "843-849"xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/title | "Disturbed pyloric motility in Ws/Ws mutant rats due to deficiency of c-kit-expressing interstitial cells of Cajal."xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/9832052 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9832052 |
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