| http://purl.uniprot.org/citations/9846755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9846755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9846755 | http://www.w3.org/2000/01/rdf-schema#comment | "The early secreted antigenic target 6 kDa protein (ESAT-6) is a potent T-cell protein antigen synthesized by Mycobacterium tuberculosis. Its corresponding gene (esat-6) is located in RD1, a 10 kb DNA region deleted in the attenuated tuberculosis vaccine strain Mycobacterium bovis BCG. The promoter region of M. tuberculosis esat-6 was cloned and characterized. A new gene, designated lhp and cotranscribed with esat-6, was identified. Moreover, computer searches in the M. tuberculosis genome identified 13 genes related to the lhp/esat-6 operon, defining a novel gene family. The transcription initiation sites of the lhp/esat-6 operon were mapped using M. tuberculosis RNA. The corresponding promoter signals were not recognized in Mycobacterium smegmatis, in which transcription of lhp/esat-6 is initiated at different locations. The M. tuberculosis lhp gene product was identified as CFP-10, a low-molecular-mass protein found in the short-term culture filtrate. These results show that the genes encoding CFP-10 and ESAT-6 are transcribed together in M. tuberculosis and that both code for small exported proteins."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.org/dc/terms/identifier | "doi:10.1099/00221287-144-11-3195"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.org/dc/terms/identifier | "doi:10.1099/00221287-144-11-3195"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Berthet F.-X."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Berthet F.-X."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Gicquel B."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Gicquel B."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Andersen P."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Andersen P."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Rosenkrands I."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Rosenkrands I."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Rasmussen P.B."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/author | "Rasmussen P.B."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/name | "Microbiology"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/name | "Microbiology"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/pages | "3195-3203"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/pages | "3195-3203"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/title | "A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/title | "A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)."xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/volume | "144"xsd:string |
| http://purl.uniprot.org/citations/9846755 | http://purl.uniprot.org/core/volume | "144"xsd:string |