| http://purl.uniprot.org/citations/9853961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9853961 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9853961 | http://www.w3.org/2000/01/rdf-schema#comment | "ABmp-dependent in vitro model was used to identify cDNAs during the manifestation of mesenchymal lineages. This model involves the recombinant expression of Bmps (Bmp-2, Bmp-4-7) in murine mesenchymal C3H10T1/2 progenitors, which leads to the differentiation into three lineages: the osteogenic, the chondrogenic and the adipogenic lineage, albeit in varying efficiencies. By subtractive cloning, 21 Bmp-2-regulated cDNAs from C3H10T1/2 mesenchymal progenitors were identified; 20 were related to known sequences and 1 was not. During mouse embryonic development, many of these cDNAs are expressed in chondrogenic, osteogenic, and in adipogenic tissues. Novel findings include a G0/G1 switch gene (G0S2), which was demonstrated to be predominantly expressed in adipose tissue during late murine embryonic development. Furthermore, the membrane-standing glycoprotein autotaxin (ATX) is expressed, at precartilage condensations, joint regions, and during tooth development. An as yet undescribed cDNA, 29A, which encodes a putative secreted factor, is expressed in developing osteo-/chondrogenic tissues of vertebrae, ribs, tooth, and the limb bud. C3H10T1/2-progenitors, therefore, may serve as a legitimate model for the investigation of the Bmp-mediated events during mesenchymal differentiation."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0177(199812)213:4<398::aid-aja5>3.0.co;2-t"xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0177(199812)213:4<398::aid-aja5>3.0.co;2-t"xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Lauber J."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Lauber J."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Schroeder D."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Schroeder D."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Flohe L."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Flohe L."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Hoffmann A."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Hoffmann A."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Ahrens M."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Ahrens M."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Baechner D."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Baechner D."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Betat N."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Betat N."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Gross G."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Gross G."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Steinert P."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/author | "Steinert P."xsd:string |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9853961 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |