| http://purl.uniprot.org/citations/9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9862427 | http://www.w3.org/2000/01/rdf-schema#comment | "Alpha-synuclein (alpha-syn) protein has been found in association with the pathological lesions of a number of neurodegenerative diseases. Recently, mutations in the alpha-syn gene have been reported in families susceptible to an inherited form of Parkinson's disease. We report here that human wild-type alpha-syn, PD-linked mutant alpha-syn(Ala30Pro) and mutant alpha-syn(Ala53Thr) proteins can self-aggregate and form amyloid-like filaments. The mutant alpha-syn forms more beta-sheet and mature filaments than the wild-type protein. These findings suggest that accumulation of alpha-syn as insoluble deposits of amyloid may play a major role in the pathogenesis of these neurodegenerative diseases."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(98)01419-7"xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/author | "Curran M.D."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/author | "Jakes R."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/author | "Wallace A."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/author | "El-Agnaf O.M."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/pages | "67-70"xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/title | "Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease."xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://purl.uniprot.org/core/volume | "440"xsd:string |
| http://purl.uniprot.org/citations/9862427 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9862427 |
| http://purl.uniprot.org/citations/9862427 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9862427 |
| http://purl.uniprot.org/uniprot/#_P61626-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P61769-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_Q15582-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_A1E959-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P04279-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P06396-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P02766-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P37840-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P10997-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P01034-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |
| http://purl.uniprot.org/uniprot/#_P01160-mappedCitation-9862427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9862427 |