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http://purl.uniprot.org/citations/9883738http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9883738http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9883738http://www.w3.org/2000/01/rdf-schema#comment"Clathrin-mediated endocytosis is thought to involve the activity of the clathrin adaptor protein AP180. However, the role of this protein in endocytosis in vivo remains unknown. Here, we show that a mutation that eliminates an AP180 homolog (LAP) in Drosophila severely impairs the efficiency of synaptic vesicle endocytosis and alters the normal localization of clathrin in nerve terminals. Most importantly, the size of both synaptic vesicles and quanta is significantly increased in lap mutants. These results provide novel insights into the molecular mechanism of endocytosis and reveal a role for AP180 in regulating vesicle size through a clathrin-dependent reassembly process."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)80664-9"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)80664-9"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Zhang B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Zhang B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Bellen H.J."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Bellen H.J."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Ganetzky B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Ganetzky B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Budnik V."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Budnik V."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Koh Y.H."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Koh Y.H."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Beckstead R.B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/author"Beckstead R.B."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/pages"1465-1475"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/pages"1465-1475"xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/title"Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis."xsd:string
http://purl.uniprot.org/citations/9883738http://purl.uniprot.org/core/title"Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis."xsd:string