| http://purl.uniprot.org/citations/9888854 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9888854 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice with a targeted gene disruption of p85alpha, a regulatory subunit of phosphoinositide 3-kinase, had impaired B cell development at the pro-B cell stage, reduced numbers of mature B cells and peritoneal CD5+ Ly-1 B cells, reduced B cell proliferative responses, and no T cell-independent antibody production. These phenotypes are nearly identical to those of Btk-/- or xid (X-linked immunodeficiency) mice. These results provide evidence that p85alpha is functionally linked to the Btk pathway in antigen receptor-mediated signal transduction and is pivotal in B cell development and functions."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.283.5400.390"xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Aizawa S."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Suzuki H."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Kadowaki T."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Fujiwara M."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Terauchi Y."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Yazaki Y."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/author | "Koyasu S."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/pages | "390-392"xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/title | "Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase."xsd:string |
| http://purl.uniprot.org/citations/9888854 | http://purl.uniprot.org/core/volume | "283"xsd:string |
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