RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9895327http://www.w3.org/2000/01/rdf-schema#comment"In Caenorhabditis elegans males, a row of epidermal precursor cells called seam cells generates a pattern of cuticular alae in anterior body regions and neural sensilla called rays in the posterior. The Hox gene mab-5 is required for two posterior seam cells, V5 and V6, to generate rays. In mab-5 mutant males, V5 and V6 do not generate sensory ray lineages but instead generate lineages that lead to alae. Here we show that two independent regulatory pathways can activate mab-5 expression in the V cells. First, the caudal homolog pal-1 turns on mab-5 in V6 during embryogenesis. Second, a Wnt signaling pathway is capable of activating mab-5 in the V cells during postembryonic development; however, during normal development Wnt signaling is inhibited by signals from neighboring V cells. The inhibition of this Wnt signaling pathway by lateral signals between the V cells limits the number of rays in the animal and also determines the position of the boundary between alae and rays."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.org/dc/terms/identifier"doi:10.1242/dev.126.4.805"xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/author"Harris J.M."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/author"Maloof J.N."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/author"Kenyon C."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/author"Hunter C.P."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/name"Development"xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/pages"805-814"xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/title"Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling."xsd:string
http://purl.uniprot.org/citations/9895327http://purl.uniprot.org/core/volume"126"xsd:string
http://purl.uniprot.org/citations/9895327http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9895327
http://purl.uniprot.org/citations/9895327http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9895327
http://purl.uniprot.org/uniprot/#_A0A078BS14-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_P34766-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_G5EDV1-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_G5EG05-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_Q18825-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_O62090-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/#_Q95Y45-mappedCitation-9895327http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/O62090http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/G5EG05http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/Q95Y45http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/9895327
http://purl.uniprot.org/uniprot/Q18825http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/9895327