| http://purl.uniprot.org/citations/9918847 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9918847 | http://www.w3.org/2000/01/rdf-schema#comment | "Marked osteopetrosis is observed only in mi/mi mutant mice although normal osteoclastgenesis is observed in other mutant mice including null mutants at the mi locus. Mutant microphthalmia-associated transcription factor (mi-MITF) has defective nuclear localization potential. We found normal MITF (+-MITF)-c-Fos and mi-MITF-c-Fos complexes in the cytoplasm by immunoblotting, and showed that PU.1 bound with both +-MITF and mi-MITF using an electrophoretic mobility shift assay. Furthermore, the nuclear localization of PU.1 and c-Fos was inhibited by over-expressed mi-MITF in WEHI-3 cells. These results indicate that mi-MITF expressing in osteoclasts specifically binds to c-Fos and PU.1 which are essential transcription factors of osteoclastgenesis and that mi-MITF blocks the nuclear localization of these other transcription factors, which may result in osteopetrosis in mi/mi mutant mice."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1998.9918"xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Kitamura Y."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Sato M."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Nomura S."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Ochi T."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Morii E."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Yasui N."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/author | "Takebayashi-Suzuki K."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/pages | "384-387"xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/title | "Microphthalmia-associated transcription factor interacts with PU.1 and c-Fos: determination of their subcellular localization."xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://purl.uniprot.org/core/volume | "254"xsd:string |
| http://purl.uniprot.org/citations/9918847 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9918847 |
| http://purl.uniprot.org/citations/9918847 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9918847 |
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| http://purl.uniprot.org/uniprot/#_A0A5H1ZRM6-mappedCitation-9918847 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9918847 |
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| http://purl.uniprot.org/uniprot/#_Q08874-mappedCitation-9918847 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9918847 |
| http://purl.uniprot.org/uniprot/#_Q5C9J0-mappedCitation-9918847 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9918847 |