http://purl.uniprot.org/citations/9990008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9990008 | http://www.w3.org/2000/01/rdf-schema#comment | "The pyruvate dehydrogenase multienzyme complex (Mr of 5-10 million) is assembled around a structural core formed of multiple copies of dihydrolipoyl acetyltransferase (E2p), which exhibits the shape of either a cube or a dodecahedron, depending on the source. The crystal structures of the 60-meric dihydrolipoyl acyltransferase cores of Bacillus stearothermophilus and Enterococcus faecalis pyruvate dehydrogenase complexes were determined and revealed a remarkably hollow dodecahedron with an outer diameter of approximately 237 A, 12 large openings of approximately 52 A diameter across the fivefold axes, and an inner cavity with a diameter of approximately 118 A. Comparison of cubic and dodecahedral E2p assemblies shows that combining the principles of quasi-equivalence formulated by Caspar and Klug [Caspar, D. L. & Klug, A. (1962) Cold Spring Harbor Symp. Quant. Biol. 27, 1-4] with strict Euclidean geometric considerations results in predictions of the major features of the E2p dodecahedron matching the observed features almost exactly."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.96.4.1240"xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Perham R.N."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Hol W.G."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Allen M.D."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Izard T."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Aevarsson A."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "Westphal A.H."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/author | "de Kok A."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/pages | "1240-1245"xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/title | "Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes."xsd:string |
http://purl.uniprot.org/citations/9990008 | http://purl.uniprot.org/core/volume | "96"xsd:string |
http://purl.uniprot.org/citations/9990008 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9990008 |
http://purl.uniprot.org/citations/9990008 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9990008 |
http://purl.uniprot.org/uniprot/#_P11961-mappedCitation-9990008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9990008 |
http://purl.uniprot.org/uniprot/P11961 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9990008 |