http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.14.11.- |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.-.-.- |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.14.-.- |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#comment | "It can also demethylate monomethylated (but not the trimethylated) Lys(36), cf. EC 1.14.11.69."xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#comment | "Of the seven potential methylation sites in histones H3 (K4, K9, K27, K36, K79) and H4 (K20, R3) from HeLa cells, the enzyme is specific for Lys(36)."xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#comment | "Requires iron(II)."xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#comment | "Lysine residues exist in three methylation states (mono-, di- and trimethylated)."xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2000/01/rdf-schema#comment | "The enzyme preferentially demethylates the dimethyl form of Lys(36) (K36me2), which is its natural substrate, to form the monomethylated and unmethylated forms of Lys(36)."xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#prefLabel | "[histone H3]-dimethyl-L-lysine(36) demethylase"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16362057 |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "histone demethylase"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "JHDM1A"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "H3-K36-specific demethylase"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "JmjC domain-containing histone demethylase 1A"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "[histone-H3]-lysine-36 demethylase"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#altLabel | "histone-lysine (H3-K36) demethylase"xsd:string |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://purl.uniprot.org/core/activity | http://purl.uniprot.org/enzyme/1.14.11.27#SIPA9EAE6F4292C80C4 |
http://purl.uniprot.org/enzyme/1.14.11.27 | http://www.w3.org/2004/02/skos/core#broaderTransitive | http://purl.uniprot.org/enzyme/1.14.11.- |
http://purl.uniprot.org/uniprot/A0A815H0S9 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.14.11.27 |
http://purl.uniprot.org/uniprot/A0AA39QHD6 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.14.11.27 |
http://purl.uniprot.org/uniprot/Q7PYH2 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.14.11.27 |
http://purl.uniprot.org/uniprot/A0A8S3RG52 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.14.11.27 |
http://purl.uniprot.org/uniprot/A0A814DK05 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.14.11.27 |