| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Enzyme |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.5.-.- |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.-.-.- |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/1.5.1.- |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Enzyme |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#comment | "The enzyme from yeast and mammals catalyzes a physiologically irreversible reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using NADPH as the electron donor."xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#comment | "A flavoprotein (FAD)."xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#comment | "It plays an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis."xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2000/01/rdf-schema#comment | "The enzyme contains an N-terminal catalytic domain and a C-terminal allosteric regulatory domain that binds S-adenosyl-L-methionine, which acts as an inhibitor. cf. EC 1.5.1.54, EC 1.5.1.20, and EC 1.5.7.1."xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#prefLabel | "methylenetetrahydrofolate reductase (NADPH)"xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11729203 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/29891918 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/13817476 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2383427 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/4399897 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/6975779 |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#altLabel | "5,10-methylenetetrahydrofolate reductase (NADPH)"xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#altLabel | "5,10-methylenetetrahydrofolate reductase (FADH2)"xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#altLabel | "5,10-CH2-H4folate reductase"xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#altLabel | "N(5),10-methylenetetrahydrofolate reductase"xsd:string |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://purl.uniprot.org/core/activity | http://purl.uniprot.org/enzyme/1.5.1.53#SIP05070A6503E0469A |
| http://purl.uniprot.org/enzyme/1.5.1.53 | http://www.w3.org/2004/02/skos/core#broaderTransitive | http://purl.uniprot.org/enzyme/1.5.1.- |
| http://purl.uniprot.org/uniprot/A0A821IHH0 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.5.1.53 |
| http://purl.uniprot.org/uniprot/A0A811YP59 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.5.1.53 |
| http://purl.uniprot.org/uniprot/A0A8C4HDD2 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/1.5.1.53 |