http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.7.11.- |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.7.-.- |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.-.-.- |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#comment | "Subsequent degradation of the IkappaB complex (IKK) activates NF-kappaB, a translation factor that plays an important role in inflammation, immunity, cell proliferation and apoptosis."xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphorylates IkappaB proteins at specific serine residues, which marks them for destruction via the ubiquitination pathway."xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2000/01/rdf-schema#comment | "If the serine residues are replaced by threonine residues, the activity of the enzyme is decreased considerably."xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#prefLabel | "IkappaB kinase"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9244310 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9346484 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15653325 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9346241 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "IKBKB"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "TBK1"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "CHUK"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "TANK-binding kinase 1"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "IKK"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "IKBKA"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "IKK-1"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "IKK-2"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#altLabel | "inhibitor of NFkappaB kinase"xsd:string |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/replaces | http://purl.uniprot.org/enzyme/2.7.1.37 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://purl.uniprot.org/core/activity | http://purl.uniprot.org/enzyme/2.7.11.10#SIP3F7934B9151D3683 |
http://purl.uniprot.org/enzyme/2.7.11.10 | http://www.w3.org/2004/02/skos/core#broaderTransitive | http://purl.uniprot.org/enzyme/2.7.11.- |