http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/3.4.-.- |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/3.4.22.- |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/3.-.-.- |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Enzyme |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#comment | "Caspase-6 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60)."xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#comment | "Can also cleave and inactivate lamins, the intermediate filament scaffold proteins of the nuclear envelope, leading to nuclear fragementation in the final phases of apoptosis."xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#comment | "Caspase-6 can cleave its prodomain to produce mature caspase-6, which directly activates caspase-8 (EC 3.4.22.61) and leads to cytochrome c release from the mitochondria; the release of cytochrome c, which is an essential component of the intrinsic apoptosis pathway."xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#comment | "Belongs to peptidase family C14."xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2000/01/rdf-schema#comment | "These caspases are responsible for the proteolysis of the majority of cellular polypeptides, [e.g. poly(ADP-ribose) polymerase (PARP)], which lead to the apoptotic phenotype."xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2004/02/skos/core#prefLabel | "caspase-6"xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11104820 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12049625 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12089322 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12232792 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16518869 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8710882 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2004/02/skos/core#altLabel | "Mch2"xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2004/02/skos/core#altLabel | "CASP-6"xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2004/02/skos/core#altLabel | "apoptotic protease Mch-2"xsd:string |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://purl.uniprot.org/core/activity | http://purl.uniprot.org/enzyme/3.4.22.59#SIPD0BB5CAEC87955E8 |
http://purl.uniprot.org/enzyme/3.4.22.59 | http://www.w3.org/2004/02/skos/core#broaderTransitive | http://purl.uniprot.org/enzyme/3.4.22.- |
http://purl.uniprot.org/uniprot/A0A093J577 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/3.4.22.59 |
http://purl.uniprot.org/uniprot/A0A3Q2DMY8 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/3.4.22.59 |
http://purl.uniprot.org/uniprot/A0A9Q0YJ48 | http://purl.uniprot.org/core/enzyme | http://purl.uniprot.org/enzyme/3.4.22.59 |