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http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Enzyme
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.4.-.-
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.4.22.-
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.-.-.-
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/core/Enzyme
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#comment"Caspase-6 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60)."xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#comment"Can also cleave and inactivate lamins, the intermediate filament scaffold proteins of the nuclear envelope, leading to nuclear fragementation in the final phases of apoptosis."xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#comment"Caspase-6 can cleave its prodomain to produce mature caspase-6, which directly activates caspase-8 (EC 3.4.22.61) and leads to cytochrome c release from the mitochondria; the release of cytochrome c, which is an essential component of the intrinsic apoptosis pathway."xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#comment"Belongs to peptidase family C14."xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2000/01/rdf-schema#comment"These caspases are responsible for the proteolysis of the majority of cellular polypeptides, [e.g. poly(ADP-ribose) polymerase (PARP)], which lead to the apoptotic phenotype."xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2004/02/skos/core#prefLabel"caspase-6"xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11104820
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12049625
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12089322
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12232792
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/16518869
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8710882
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2004/02/skos/core#altLabel"Mch2"xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2004/02/skos/core#altLabel"CASP-6"xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2004/02/skos/core#altLabel"apoptotic protease Mch-2"xsd:string
http://purl.uniprot.org/enzyme/3.4.22.59http://purl.uniprot.org/core/activityhttp://purl.uniprot.org/enzyme/3.4.22.59#SIPD0BB5CAEC87955E8
http://purl.uniprot.org/enzyme/3.4.22.59http://www.w3.org/2004/02/skos/core#broaderTransitivehttp://purl.uniprot.org/enzyme/3.4.22.-
http://purl.uniprot.org/uniprot/A0A093J577http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.4.22.59
http://purl.uniprot.org/uniprot/A0A3Q2DMY8http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.4.22.59
http://purl.uniprot.org/uniprot/A0A9Q0YJ48http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.4.22.59