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http://purl.uniprot.org/keywords/1092http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Concept
http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/keywords/945
http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/keywords/1090
http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/keywords/899
http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/keywords/1113
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http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#comment"Viral protein involved in the evasion of host innate defense by inhibiting the interferon regulatory factor-3 (IRF3) protein. Viral infection triggers the phosphorylation and activation of IRF3. The activated IRF3 migrates to the nucleus, where it complexes with the transcription coactivator CREBBP/EP300, leading to the transcriptional activation of the IFN-alpha and IFN-beta genes. Several viral proteins directly bind to IRF3 and inhibit its transcriptional activity while others target it to the proteasome for degradation."xsd:string
http://purl.uniprot.org/keywords/1092http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.obolibrary.org/obo/GO_0039548
http://purl.uniprot.org/keywords/1092http://www.w3.org/2004/02/skos/core#prefLabel"Inhibition of host IRF3 by virus"xsd:string
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