http://purl.uniprot.org/keywords/1224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Concept |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/keywords/945 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/keywords/1090 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/keywords/899 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/keywords/1113 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Concept |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/keywords/9999 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#comment | "Viral protein involved in the evasion of host innate defenses by inhibiting the IKBKE/IKK-epsilon kinase. Upon viral infection, the DDX58/RIG-I or IFIH1/MDA5 receptors recognize foreign material and transmit the signal to downstream components MAVS and IKBKE. In turn, the IKBKE kinase phosphorylates and activates IRF3 and/or IRF7. Once phosphorylated, IRF3 and IRF7 translocate into the nucleus to drive transcription of interferons. Several viruses including arenaviruses or ebola virus interact directly with and inhibit IKBKE/IKK-epsilon to prevent IRFs activation."xsd:string |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.obolibrary.org/obo/GO_0039724 |
http://purl.uniprot.org/keywords/1224 | http://www.w3.org/2004/02/skos/core#prefLabel | "Inhibition of host IKBKE by virus"xsd:string |
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http://purl.uniprot.org/uniprot/A0A0U1ZV20 | http://purl.uniprot.org/core/classifiedWith | http://purl.uniprot.org/keywords/1224 |
http://purl.uniprot.org/uniprot/A0A0U1ZVH0 | http://purl.uniprot.org/core/classifiedWith | http://purl.uniprot.org/keywords/1224 |
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