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http://purl.uniprot.org/keywords/169http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Concept
http://purl.uniprot.org/keywords/169http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/core/Concept
http://purl.uniprot.org/keywords/169http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/keywords/9999
http://purl.uniprot.org/keywords/169http://www.w3.org/2000/01/rdf-schema#comment"Protein involved in the synthesis of cobalamin. Cobalamin, which is synthesized by microorganisms, has equatorial sites occupied by a modified porphyrin ring system, with two of the four pyrrol rings fused directly (without an intervening methine bridge). The modified porphyrin system binds a cobalt(III) ion in the center, and this is called a corrin ring system. One axial site is occupied usually by an intramolecularly-bound dimethylbenzimidazole nucleotide and the other axial site is occupied by a number of different ligands such as water (aquacobalamin), cyanide (cyanocobalamine=vitamin B12), glutathione (glutathionylcobalamine), 5'deoxyadenosine (adenosylcobalamine=coenzyme B12) or a methyl group (methylcobalamin). Vitamin B12, for instance, is a prosthetic group of certain mammalian enzymes, where it is essential for the normal maturation and development of erythrocytes. A deficiency in the diet or more frequently the failure to absorb the vitamin B12 give rise to pernicious anemia."xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.obolibrary.org/obo/GO_0009236
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#prefLabel"Cobalamin biosynthesis"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Cobalamin synthesis"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Cobalamin anabolism"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Cobalamin biosynthetic process"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Cobalamin formation"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Vitamin B12 anabolism"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Vitamin B12 biosynthesis"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Vitamin B12 biosynthetic process"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Vitamin B12 formation"xsd:string
http://purl.uniprot.org/keywords/169http://www.w3.org/2004/02/skos/core#altLabel"Vitamin B12 synthesis"xsd:string
http://purl.uniprot.org/keywords/169http://purl.uniprot.org/core/categoryhttp://purl.uniprot.org/keywords/9999
http://purl.uniprot.org/uniprot/A0AA52CTD0http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A940NAC8http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A0D9A8I2http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A099L7W5http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A938C9P8http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A963D8R3http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A843J9H1http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A843E880http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169
http://purl.uniprot.org/uniprot/A0A9D8U138http://purl.uniprot.org/core/classifiedWithhttp://purl.uniprot.org/keywords/169