| http://purl.uniprot.org/keywords/977 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein which, if defective, causes ichthyosis, any of a group of cutaneous disorders characterized by increased or aberrant keratinization and resulting in non-inflammatory scaling of the skin. Most ichthyoses are genetically determined, while some may be acquired and develop in association with various systemic diseases or be a prominent feature in certain genetic syndromes."xsd:string |