| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Proteome |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2000/01/rdf-schema#comment | "Shigella is a Gram-negative, non-sporulating, facultative anaerobe bacterium that causes dysentery or shigellosis in man. Shigella are highly invasive in the colon and the rectum, and are able to proliferate in the host cell cytoplasm, triggering an inflammatory reaction. Shigella was recognized as the etiologic agent for bacillary dysentery in the 1890's, and adopted as a genus in the 1950's and subgrouped into four species. However, a recent genetic study argues that Shigella emerged from multiple independent origins of E.coli 35,000-270,000 years ago and may not constitute a genus. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material. A new Chinese serotype of S. flexneri appeared in 2001 and replaced serotype 2a in 2003 as the most prevalent serotype in Henan Province. The new serotype also became the dominant serotype in 7 of the 10 other provinces under surveillance in China by 2007. It is a new variant of serotype X, and this clinical isolate 2002017 is an example. The genetic basis of serotype conversion by the acquisition of an SfX bacteriophage was identified in this study. By comparing various data a novel mechanism of epidemic persistence of S. flexneri over long periods through serotype switching to escape infection-induced immunity has been identified (adapted from PMID 19955273)."xsd:string |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000001884#assembly |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000001884#source |
| http://purl.uniprot.org/proteomes/UP000001884 | http://purl.uniprot.org/core/organism | http://purl.uniprot.org/taxonomy/591020 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/19955273 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#closeMatch | http://purl.uniprot.org/proteomes/UP000001884#cpd |
| http://purl.uniprot.org/proteomes/UP000001884 | http://purl.org/dc/terms/modified | "2023-01-26"xsd:date |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Chromosome |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Plasmid%20pSFxv_3 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Plasmid%20pSFxv_1 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Plasmid%20pSFxv_2 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Plasmid%20pSFxv_5 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000001884#Plasmid%20pSFxv_4 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://busco.ezlab.org/schema#has_score | http://purl.uniprot.org/proteomes/UP000001884#busco |
| http://purl.uniprot.org/proteomes/UP000001884 | http://purl.uniprot.org/core/panproteome | http://purl.uniprot.org/proteomes/UP000000625 |
| http://purl.uniprot.org/proteomes/UP000001884 | http://purl.uniprot.org/core/strain | http://purl.uniprot.org/proteomes/UP000001884#2002017 |
| http://purl.uniprot.org/uniprot/D2AG56#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AIJ3#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AJ04#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AB12#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AGV3#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AEP7#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2AED5#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |
| http://purl.uniprot.org/uniprot/D2A7R2#attribution-673783D36BE8EAE66165888591A323E2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000001884 |