| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Proteome |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2000/01/rdf-schema#comment | "Providencia stuartii is the most common Providencia species capable of causing human infections. It is an opportunistic pathogen seen in patients with severe burns or long-term indwelling urinary catheters. In animals, P. stuartii infections can cause neonatal diarrhea in dairy cows. In humans, P. stuartii can be isolated from urine (most common), stool, and blood, as well as from sputum, skin, and wound cultures. P. stuartii septicemia is primarily of urinary origin. It is the most common cause of purple urine bag syndrome. Upon physical examination, P. stuartii bloodstream infection is associated with fever, tachycardia, and hypotension. Potent carbapenemase activity and resistance to clinical beta-lactamase inhibitors, combined with increasing association with highly mobile genetic elements makes metallo-beta-lactamase one of the most serious challenges facing infection control programs in recent years. The metallo-beta-lactamase, New Delhi metallo-beta-lactamase 1 (blaNDM-1), constitutes a case study in the epidemiology of metallo-beta-lactamase transmission. Like the VIM-type metallo-beta-lactamases, NDM-1 confers resistance to all beta-lactam agents except the monobactams, but mobile DNA elements associated with blaNDM-1 transmission routinely encode numerous other antibiotic resistance genes, including resistance to monobactams. BlaNDM-1 is found in an ever-widening number of bacterial species and is strongly associated with large, highly mobile plasmids that encode numerous other antibiotic resistance genes. Providencia stuartii (strain MRSN 2154) is an pathogenic, Gram-negative bacterium isolated from the blood of a burn patient in a US/Coalition medical facility in Afghanistan. Most P. stuartii infections are of nosocomial origin and this bacterium is resistant to carbapenems (ertapenem, imipenem, and meropenem), and susceptible to the monobactam, aztreonam. In P. stuartii, blaNDM-1 is carried on a large plasmid, pMR0211. The plasmid consists of a backbone with considerable homology to pAR060302 from E. coli, and retains many of the antibiotic resistance genes associated with it. (Adapted from PMID: 22290972 and http://fr.wikipedia.org/wiki/Providencia_%28genre%29)."xsd:string |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000005012#assembly |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000005012#source |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/organism | http://purl.uniprot.org/taxonomy/1157951 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/SIPD739765DDD4B6237 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/22290972 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/22740665 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2004/02/skos/core#closeMatch | http://purl.uniprot.org/proteomes/UP000005012#cpd |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.org/dc/terms/modified | "2023-07-27"xsd:date |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000005012#Plasmid%20pMR0211 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000005012#Chromosome |
| http://purl.uniprot.org/proteomes/UP000005012 | http://busco.ezlab.org/schema#has_score | http://purl.uniprot.org/proteomes/UP000005012#busco |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/panproteome | http://purl.uniprot.org/proteomes/UP000078224 |
| http://purl.uniprot.org/proteomes/UP000005012 | http://purl.uniprot.org/core/strain | http://purl.uniprot.org/proteomes/UP000005012#MRSN%202154 |
| http://purl.uniprot.org/uniprot/A0A140NHB8#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140STD4#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NKA6#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NKV9#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NJV7#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NJ36#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NKR2#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NEG0#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NTF9#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |
| http://purl.uniprot.org/uniprot/A0A140NKT1#attribution-E095FD4143508022B5C4F8C612B6B04E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/proteomes/UP000005012 |