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http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Proteome
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2000/01/rdf-schema#comment"Borreliae, the causative agent of Lyme disease, are obligatorily bound to their host organisms for survival. During their life cycle they switch from the invertebrate host tick (Ixodes spec.) to various vertebrate hosts via a tick bite. It seems that Borellia have three indispensable components; a chromosome, a circular plasmid of approximately 26 kb (cp27 in B.afzelli) and a linear plasmid of approximately 54 kb (lp60-1 in B.afzelli), each species can also contain many other plasmids. The range of vertebrates and invertebrates used as hosts is thought to be mediated by factors encoded mainly on a large number of different plasmids found in Borreliae genomes. These plasmids are characterized by their wealth of paralogous genes. It is thought that Borreliae plasmids are not stable and are frequently rearranged leading to differing plasmid content within a species. The chromosome is also involved in fission/fusion events, and the right end of the chromosome of B. burgdorferi strains is variable due to its ability to catch plasmids. During passage plasmids can be lost due to the lack of selection pressure, which can be accompanied by the inability of Borreliae to prosper in the host. "xsd:string
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2000/01/rdf-schema#comment"B.afzelii Pko was originally isolated from human skin, and the early passage (8th) is infectious in gerbils. It was first incompletely sequenced in 2006, which was made up of early (8th) and late (70th) passage sequences; in the late passage the vls gene locus encoding for variable surface proteins is missing, which probably accounts for the fragmentary nature of plasmid lp31. The plasmids contribute at least 36% of the total genome; there are probably 9 circular and 7 linear plasmids, not all of which have been closed. It was sequenced again, this time fully, in 2011."xsd:string
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000005216#assembly
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000005216#source
http://purl.uniprot.org/proteomes/UP000005216http://purl.uniprot.org/core/organismhttp://purl.uniprot.org/taxonomy/390236
http://purl.uniprot.org/proteomes/UP000005216http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/22123755
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#closeMatchhttp://purl.uniprot.org/proteomes/UP000005216#cpd
http://purl.uniprot.org/proteomes/UP000005216http://purl.org/dc/terms/modified"2023-03-06"xsd:date
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Chromosome
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp17
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp54
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-5
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-9
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp38
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp32-10
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp28-2
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-11
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-12
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-3
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp32-7
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20cp26
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp28-4
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp28-7
http://purl.uniprot.org/proteomes/UP000005216http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000005216#Plasmid%20lp28-3