| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Proteome |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2000/01/rdf-schema#comment | "Escherichia coli is a Gram-negative straight rod, which either uses peritrichous flagella for mobility or is nonmotile. It is a facultatively anaerobic chemoorganotroph capable of both respiratory and fermentative metabolism. E.coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesising appreciable amounts of vitamins. It is an important component of the biosphere. It colonizes the lower gut of animals and survives when released to the natural environment, allowing widespread dissemination to new hosts. Pathogenic E.coli strains are responsible for infection of the enteric, urinary, pulmonary and nervous systems. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material."xsd:string |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2000/01/rdf-schema#comment | "Clone D i2 (this entry) and D i14 (ECOC1) were isolated and fully sequenced in a study which examined a clone that persisted in a family for over 3 years. Clone D was one of two clones that caused a urinary tract infection during the course of a three-year study of E. coli in a six-member household; 5 more samples were taken from each member over the course of 3 further years. Clone D was found in one or more household members on each of the 6 sampling dates over the 3 years, and on more than one occasion in five of the six individuals. For four of these individuals clone D accounted for all 5 colonies selected from the sample at least once. The number of clone D-positive sampling dates per host was 5 (dog), 4 (daughter D1), 2 (daughter D2) and 1 (father and son), for a total of 13 of the 32 faecal samples taken. The full genome sequences obtained for i2 and i14, the first and last isolates of clone D respectively (38 months apart), differed by only 8 base substitutions. Clone i2 was a human isolate while i14 was isolated from the family dog. The 14 isolates analyzed had a total of 20 mutational base changes, and fell into 11 genotypes. The authors estimate there is an average of about 1 mutation fixed per year, about 6-fold higher than a widely accepted rate for bacteria in general. The host data also imply at least 6 host transfer events over the 3 years, with 2 lineages present over much of that period (adapted from PMID 22046404)."xsd:string |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000005865#assembly |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2000/01/rdf-schema#seeAlso | http://purl.uniprot.org/proteomes/UP000005865#source |
| http://purl.uniprot.org/proteomes/UP000005865 | http://purl.uniprot.org/core/organism | http://purl.uniprot.org/taxonomy/885276 |
| http://purl.uniprot.org/proteomes/UP000005865 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/22046404 |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2004/02/skos/core#closeMatch | http://purl.uniprot.org/proteomes/UP000005865#cpd |
| http://purl.uniprot.org/proteomes/UP000005865 | http://purl.org/dc/terms/modified | "2023-01-26"xsd:date |
| http://purl.uniprot.org/proteomes/UP000005865 | http://www.w3.org/2004/02/skos/core#narrower | http://purl.uniprot.org/proteomes/UP000005865#Chromosome |
| http://purl.uniprot.org/proteomes/UP000005865 | http://busco.ezlab.org/schema#has_score | http://purl.uniprot.org/proteomes/UP000005865#busco |
| http://purl.uniprot.org/proteomes/UP000005865 | http://purl.uniprot.org/core/redundantTo | http://purl.uniprot.org/proteomes/UP000001410 |
| http://purl.uniprot.org/proteomes/UP000005865 | http://purl.uniprot.org/core/strain | http://purl.uniprot.org/proteomes/UP000005865#'clone%20D%20i2' |