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http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Proteome
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2000/01/rdf-schema#comment"Methicillin resistant S.aureus (MRSA) ST398 strains are becoming a worldwide threat. Originally isolated from pigs, and widely distributed worldwide in livestock, ST398 strains are also found in human carriers and patients, domestic animals but also in meat products for human consumption. Recent studies reported the more promiscuous transmission of ST398 among humans; in China ST398 strains are now causing hospital acquired infections. Isolate S0385 is an ST398 strain sampled in 2006 from a blood culture of a 63 year old human endocarditis patient. It encodes a considerable accessory component, present mainly in 12 mobile genetic elements on the chromosome and in 3 plasmids that were probably acquired by horizontal gene transfer. There are 5 antibiotic resistance elements which may reflect the high antibiotic pressure prevalent in livestock farming. A putative copper resistance gene complex has also been identified; copper is used as a growth enhancer in pig farming. S.aureus is not known to easily acquire foreign DNA, however the absence of one of the known type I restriction-modification system from the chromosome suggests S0385 is less likely to degrade foreign DNA. Indeed the very variable resistance patterns of ST398 isolates suggests they may acquire foreign DNA quite easily under antibiotic pressure (adapted from PMID 19795142 and 20546576)."xsd:string
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2000/01/rdf-schema#comment"Gram-positive nonmotile coccus that grows in aerobic and anaerobic conditions, in which it forms grape-like clusters. Staphylococcus aureus is one of the major causes of community- acquired and hospital-acquired infections. It produces numerous toxins including superantigens that cause unique disease entities such as toxic-shock syndrome and staphylococcal scarlet fever. "xsd:string
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000008696#assembly
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000008696#source
http://purl.uniprot.org/proteomes/UP000008696http://purl.uniprot.org/core/organismhttp://purl.uniprot.org/taxonomy/523796
http://purl.uniprot.org/proteomes/UP000008696http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/20546576
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2004/02/skos/core#closeMatchhttp://purl.uniprot.org/proteomes/UP000008696#cpd
http://purl.uniprot.org/proteomes/UP000008696http://purl.org/dc/terms/modified"2023-01-16"xsd:date
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000008696#Chromosome
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000008696#Plasmid%20pS0385-1
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000008696#Plasmid%20pS0385-3
http://purl.uniprot.org/proteomes/UP000008696http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000008696#Plasmid%20pS0385-2
http://purl.uniprot.org/proteomes/UP000008696http://busco.ezlab.org/schema#has_scorehttp://purl.uniprot.org/proteomes/UP000008696#busco
http://purl.uniprot.org/proteomes/UP000008696http://purl.uniprot.org/core/redundantTohttp://purl.uniprot.org/proteomes/UP000221735
http://purl.uniprot.org/proteomes/UP000008696http://purl.uniprot.org/core/strainhttp://purl.uniprot.org/proteomes/UP000008696#MRSA%20ST398%20%2F%20isolate%20S0385