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http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Proteome
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2000/01/rdf-schema#comment"Chlamydia trachomatis infection is an important cause of preventable blindness and sexually transmitted disease (STD) in humans. There are 15 serovariants that exhibit distinct organotropism for the eye or the urogenital tract and are separated according to the pathobiotypes. Trachoma biovariants consist of serovars A, B, Ba, C, D, E, F, G, H, I, J and K. LGV (Lymphogranuloma venereum) biovariants consist of serovars L1, L2 and L3. Trachoma biovariants are noninvasive and epitheliotropic strains that cause blinding trachoma (A to C) or sexually transmitted diseases. LGV biovariants cause sexually transmitted diseases with disseminating infection of draining regional lymph nodes. The trpBA operon encoding tryptophan synthase is functional in STD serovars, whereas trpBA harbors mutations that inactivate the enzyme in ocular serovars. Chlamydia trachomatis is an obligate intracellular parasite depending on the host machinery for ATP synthesis. Chlamydial life cycle comprehends an intracellular metabolically- active "reticular body" and an inert extracellular spore-like "elementary body" equipped with a unique disulfide-cross-linked protein envelope. "xsd:string
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2000/01/rdf-schema#comment"Strain A2497 was isolated from a 2.5-year-old with intense active trachoma in Tanzania. Naturally occurring or antibiotic-cured nontrachoma plasmid-deficient strains are attenuated in mouse models of genital tract infection, implicating the plasmid as a key chlamydial virulence factor. This study demonstrates that a plasmid-deficient trachoma strain is highly attenuated for nonhuman primates but induces an immunity that protects against trachoma (adapted from PMID 21987657) The chromosome has been sequenced and submitted twice, but the plasmid has only been submitted once."xsd:string
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000009287#assembly
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2000/01/rdf-schema#seeAlsohttp://purl.uniprot.org/proteomes/UP000009287#source
http://purl.uniprot.org/proteomes/UP000009287http://purl.uniprot.org/core/organismhttp://purl.uniprot.org/taxonomy/580047
http://purl.uniprot.org/proteomes/UP000009287http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/21987657
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2004/02/skos/core#closeMatchhttp://purl.uniprot.org/proteomes/UP000009287#cpd
http://purl.uniprot.org/proteomes/UP000009287http://purl.org/dc/terms/modified"2023-03-06"xsd:date
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000009287#Chromosome
http://purl.uniprot.org/proteomes/UP000009287http://www.w3.org/2004/02/skos/core#narrowerhttp://purl.uniprot.org/proteomes/UP000009287#Plasmid%200001
http://purl.uniprot.org/proteomes/UP000009287http://busco.ezlab.org/schema#has_scorehttp://purl.uniprot.org/proteomes/UP000009287#busco
http://purl.uniprot.org/proteomes/UP000009287http://purl.uniprot.org/core/panproteomehttp://purl.uniprot.org/proteomes/UP000000431
http://purl.uniprot.org/proteomes/UP000009287http://purl.uniprot.org/core/strainhttp://purl.uniprot.org/proteomes/UP000009287#A2497
http://purl.uniprot.org/uniprot/G4NMB4#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMX2#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMB8#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMA5#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NM66#attribution-DE32142F82EC865860CF2BCFB3917503http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NN16#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMP2#attribution-DE32142F82EC865860CF2BCFB3917503http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NPE5#attribution-DE32142F82EC865860CF2BCFB3917503http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMK2#attribution-C8AF1B70114AD9A51620938359C70ACBhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NM58#attribution-DE32142F82EC865860CF2BCFB3917503http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287
http://purl.uniprot.org/uniprot/G4NMC8#attribution-DE32142F82EC865860CF2BCFB3917503http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/proteomes/UP000009287