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Entry version 156 (11 Dec 2019)
Sequence version 2 (02 Feb 2004)
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Protein

Otefin

Gene

Ote

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inner nuclear membrane protein (PubMed:2186029, PubMed:9199347, PubMed:18410727, PubMed:22751930). Involved in the attachment of membrane vesicles to chromatin during nuclear assembly, and is probably required for centrosome maturation and cell cycle progression during mitosis (PubMed:9199347, PubMed:22751930). Essential for differentiation of certain tissues and the maintenance of progenitor cell populations (PubMed:18410727, PubMed:24700158, PubMed:23806619, PubMed:27174470). Required for the differentiation and maintenance of male and female germline stem cells (GSCs), as well as the maintenance of somatic cells in the GSC niche (PubMed:18410727, PubMed:23806619, PubMed:27174470). This role is likely to be independent of the BMP (Dpp) pathway that negatively regulates bam transcription during GSC differentiation (PubMed:18410727, PubMed:23806619). During development, plays essential and redundant functions with the other LEM domain proteins; bocks and MAN1 (PubMed:24700158). Also has a redundant but important role with bocks during larval development (PubMed:24700158).7 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • transcription corepressor activity Source: FlyBase
  • transcription factor binding Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Mitosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Otefin1 Publication
Alternative name(s):
LEM domain-containing protein OtefinCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ote1 PublicationImported
ORF Names:CG5581Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0266420 Ote

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Cytoskeleton, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No obvious phenotype (PubMed:18410727, PubMed:23806619, PubMed:24700158). However females are sterile and aging males become prematurely sterile (PubMed:18410727, PubMed:23806619). Males and females exhibit a range of defects in their germarium that may be age dependent phenotypes (PubMed:18410727, PubMed:23806619, PubMed:27174470). Most phenotypes result from defects in germline stem cell (GSC) differentiation that often lead to GSC loss (PubMed:23806619, PubMed:27174470). Also affects somatic cells of the ovarian stem cell niche, with delayed terminal filament formation and cap cell loss (PubMed:27174470). In 10 day old males, stem cell niches display a decrease in hub cell number but somatic cyst stem cells are unaffected (PubMed:27174470). No significant decrease in adult survival, however double mutants with either bocks or Man1 do not survive to the adult stage (PubMed:24700158). Double bocks and Ote mutant larvae have small brains, their imaginal disks are reduced in size or absent, and only 10% of second-instar larvae reach the pupal stage (PubMed:24700158). In Ote and MAN1 double mutants, pupal survival and larval development is unaffected (PubMed:24700158).4 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi54S → A: Loss of phosphorylation by Cdk1. 1 Publication1
Mutagenesisi63T → A: Prevents phosphorylation and displays an increase in the number of mitotic cells. 1 Publication1
Mutagenesisi63T → E: Phosphomimetic mutant which displays a decrease in the number of mitotic cells. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002061511 – 424OtefinAdd BLAST424

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei44Phosphoserine2 Publications1
Modified residuei50Phosphoserine2 Publications1
Modified residuei54Phosphoserine1 Publication1
Modified residuei63Phosphothreonine1 Publication1
Modified residuei152Phosphoserine1 Publication1
Modified residuei192Phosphoserine1 Publication1
Modified residuei198Phosphoserine1 Publication1
Modified residuei321Phosphoserine1 Publication1
Modified residuei324Phosphothreonine1 Publication1
Modified residuei326Phosphoserine1 Publication1
Modified residuei358Phosphothreonine1 Publication1
Modified residuei378Phosphoserine2 Publications1
Modified residuei385Phosphoserine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation at Thr-63 by aurA may be required for exit from mitosis (PubMed:22751930). May be phosphorylated by Cdk1 and Pka-C1 (PubMed:9199347).2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P20240

PRoteomics IDEntifications database

More...
PRIDEi
P20240

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P20240

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in all cell types of the germarium and testis (PubMed:18410727, PubMed:27174470). Expressed in nurse cells, follicle cells and oocytes (PubMed:9199347).3 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Relatively high levels of expression in eggs and 1st instar larvae compared to pupal and adult stages, with weak expression in 2nd instar larvae (at protein level) (PubMed:16439308). Expressed throughout development in all somatic cells (PubMed:9199347). Highest levels of expression in embryos and weak expression in larvae and adults (PubMed:2186029, PubMed:9199347). Expressed throughout development (at protein level) (PubMed:2517292).4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0266420 Expressed in 32 organ(s), highest expression level in embryo

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P20240 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Med (PubMed:18410727).

Interacts with Lam (PubMed:9632815, PubMed:22751930).

Interacts with aurA, alphaTub84B, gammaTub23C and gammaTub37C (PubMed:22751930).

3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
62771, 25 interactors

Protein interaction database and analysis system

More...
IntActi
P20240, 3 interactors

Molecular INTeraction database

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MINTi
P20240

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0085947

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 30LEMPROSITE-ProRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 50Required for binding to Med and germline stem cell maintenance1 PublicationAdd BLAST50
Regioni271 – 400Required for binding to Med1 PublicationAdd BLAST130
Regioni400 – 424Essential for nuclear membrane localization and germline stem cell maintenance1 PublicationAdd BLAST25
Regioni406 – 424Essential for nuclear membrane localization1 PublicationAdd BLAST19

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi92 – 99Nuclear localization signalSequence analysis8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi151 – 155Ser/Thr-rich5
Compositional biasi228 – 233Ser/Thr-rich6
Compositional biasi268 – 272Ser/Thr-rich5
Compositional biasi307 – 311Ser/Thr-rich5

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JJE3 Eukaryota
ENOG41116GX LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000067345

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P20240

Identification of Orthologs from Complete Genome Data

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OMAi
TTTYEYK

Database of Orthologous Groups

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OrthoDBi
1019223at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P20240

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03020 LEM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00540 LEM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF63451 SSF63451, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50954 LEM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P20240-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADVDDFDSL SNAELRAKML AQGLPNIPVT DSSRKVLVKR LRASIGGQAS
60 70 80 90 100
PAASPKKTNR RETLAPAPGA PSAPAAASTP VDKLDGNKVA PATKARRTIT
110 120 130 140 150
AAEAKEPVRR LPEEAIRRRP DEADRLRSEE PVAARKPTTA PAAQPVQTRR
160 170 180 190 200
TSTSSGSERK VVEPLRKPET IVEQPASSKR ADREENYLKV NSLIVLESDE
210 220 230 240 250
EEDEQLVQAA DLVEQEHAAR QKTTKLASSG TTTYEYKSKV VEPPRRQVYE
260 270 280 290 300
ATAAPVLPPS VPSARAQTTS STRSYDYASN PAPGRYSSFV RTAAQGYVTA
310 320 330 340 350
EAPPVASYSS SYKRTYANEL SDDTDSKEDQ YESTFARNLA RLRAERIGDR
360 370 380 390 400
ISPYSRRTLA SGNAGSGSLG YEPRARRSLR PNDNSVSEAF NRWLNSLEQK
410 420
YHIKSKLFIV LLVLLLIGVY YIFY
Length:424
Mass (Da):46,584
Last modified:February 2, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i51E3A83284F7988B
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA35530 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti116I → V in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti121D → E in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti128S → P in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti141P → S in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti151T → S in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti186N → K in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti254A → S in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti292T → H in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti344A → S in CAA35530 (PubMed:10731132).Curated1
Sequence conflicti412L → V in CAA35530 (PubMed:10731132).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF57722.3
AY051940 mRNA Translation: AAK93364.1
X17495 mRNA Translation: CAA35530.1 Different initiation.

Protein sequence database of the Protein Information Resource

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PIRi
A35360

NCBI Reference Sequences

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RefSeqi
NP_476664.2, NM_057316.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0086768; FBpp0085947; FBgn0266420

Database of genes from NCBI RefSeq genomes

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GeneIDi
37090

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5581

UCSC genome browser

More...
UCSCi
CG5581-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF57722.3
AY051940 mRNA Translation: AAK93364.1
X17495 mRNA Translation: CAA35530.1 Different initiation.
PIRiA35360
RefSeqiNP_476664.2, NM_057316.5

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi62771, 25 interactors
IntActiP20240, 3 interactors
MINTiP20240
STRINGi7227.FBpp0085947

PTM databases

iPTMnetiP20240

Proteomic databases

PaxDbiP20240
PRIDEiP20240

Genome annotation databases

EnsemblMetazoaiFBtr0086768; FBpp0085947; FBgn0266420
GeneIDi37090
KEGGidme:Dmel_CG5581
UCSCiCG5581-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
37090
FlyBaseiFBgn0266420 Ote

Phylogenomic databases

eggNOGiENOG410JJE3 Eukaryota
ENOG41116GX LUCA
GeneTreeiENSGT00530000067345
InParanoidiP20240
OMAiTTTYEYK
OrthoDBi1019223at2759
PhylomeDBiP20240

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
37090

Protein Ontology

More...
PROi
PR:P20240

Gene expression databases

BgeeiFBgn0266420 Expressed in 32 organ(s), highest expression level in embryo
GenevisibleiP20240 DM

Family and domain databases

InterProiView protein in InterPro
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
PfamiView protein in Pfam
PF03020 LEM, 1 hit
SMARTiView protein in SMART
SM00540 LEM, 1 hit
SUPFAMiSSF63451 SSF63451, 1 hit
PROSITEiView protein in PROSITE
PS50954 LEM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOTE_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P20240
Secondary accession number(s): Q9V8E5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 2, 2004
Last modified: December 11, 2019
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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