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UniProtKB - Q29980 (MICB_HUMAN)

Entry version 158 (13 Nov 2019)
Sequence version 1 (01 Nov 1996)
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Protein

MHC class I polypeptide-related sequence B

Gene

MICB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAdaptive immunity, Cytolysis, Host-virus interaction, Immunity

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MHC class I polypeptide-related sequence B
Short name:
MIC-B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MICBImported
Synonyms:PERB11.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:7091 MICB

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		602436 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q29980

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini23 – 309ExtracellularSequence analysisAdd BLAST287
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Topological domaini331 – 383CytoplasmicSequence analysisAdd BLAST53

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Rheumatoid arthritis (RA)1 Publication
Disease susceptibility is associated with variations affecting the gene represented in this entry. The MICB*004 allele is associated with rheumatoid arthritis.
Disease descriptionAn inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
Related information in OMIM
Genetic variation in MICB is associated with cytomegalovirus and herpes simplex virus I seropositivity and this may be associated with schizophrenia risk.

Organism-specific databases

DisGeNET

More...DisGeNETi		4277
MIMi180300 phenotype

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA30812

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q29980

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MICB

Domain mapping of disease mutations (DMDM)

More...DMDMi		74706857

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000034141823 – 383MHC class I polypeptide-related sequence BSequence analysisAdd BLAST361

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi119 ↔ 187PROSITE-ProRule annotation1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi164N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi220N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi225 ↔ 282PROSITE-ProRule annotation1 Publication
Glycosylationi261N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Proteolytically cleaved and released from the cell surface of tumor cells.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q29980

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q29980

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q29980

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q29980

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q29980

PeptideAtlas

More...PeptideAtlasi		Q29980

PRoteomics IDEntifications database

More...PRIDEi		Q29980

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		3419
389
61282 [Q29980-1]
61283 [Q29980-3]
69573

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q29980

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q29980

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q29980

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with the exception of the central nervous system where it is absent. Expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In hepatocellular carcinomas, expressed in tumor cells but not in surrounding non-cancerous tissue.3 Publications

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By heat shock, oxidative stress, retinoic acid, IFN-alpha and the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine. Induction by IFN-alpha is impaired in patients with chronic hepatitis C virus infection. Down-regulated by human cytomegalovirus UL112 microRNA during viral infection which leads to decreased binding of KLRK1/NKG2D and reduced killing by natural killer cells.6 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000204516 Expressed in 172 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q29980 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q29980 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA064618

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Unlike classical MHC class I molecules, does not form a heterodimer with beta-2-microglobulin. Binds as a monomer to a KLRK1/NKG2D homodimer. KLRK1 forms a complex with HCST/DAP10 in which KLRK1 binds MICB while HCST acts as an adapter molecule which enables signal transduction. Receptor-ligand interaction induces clustering of both proteins in ordered structures called immune synapses and also leads to their intercellular transfer. This is associated with a reduction in the cytotoxicity of KLRK1-expressing cells.

By similarity4 Publications

(Microbial infection) Interacts with human cytomegalovirus/HHV-5 glycoprotein UL16; this interaction causes sequestration of MICB in the endoplasmic reticulum and increases resistance to KLRK1-mediated cytotoxicity.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		110424, 45 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q29980

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000252229

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1383
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q29980

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q29980

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini207 – 298Ig-like C1-typeSequence analysisAdd BLAST92

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MHC class I family. MIC subfamily.Sequence analysis

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410J8TZ Eukaryota
ENOG41118IQ LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000231246

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q29980

KEGG Orthology (KO)

More...KOi		K07985

Database of Orthologous Groups

More...OrthoDBi		1276422at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q29980

TreeFam database of animal gene trees

More...TreeFami		TF342166

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 1 hit
3.30.500.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00407 IGc1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50835 IG_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q29980-1) [UniParc]FASTAAdd to basket
Also known as: MICB11 Publication

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGLGRVLLFL AVAFPFAPPA AAAEPHSLRY NLMVLSQDES VQSGFLAEGH 
        60         70         80         90        100
LDGQPFLRYD RQKRRAKPQG QWAEDVLGAK TWDTETEDLT ENGQDLRRTL 
       110        120        130        140        150
THIKDQKGGL HSLQEIRVCE IHEDSSTRGS RHFYYDGELF LSQNLETQES 
       160        170        180        190        200
TVPQSSRAQT LAMNVTNFWK EDAMKTKTHY RAMQADCLQK LQRYLKSGVA 
       210        220        230        240        250
IRRTVPPMVN VTCSEVSEGN ITVTCRASSF YPRNITLTWR QDGVSLSHNT 
       260        270        280        290        300
QQWGDVLPDG NGTYQTWVAT RIRQGEEQRF TCYMEHSGNH GTHPVPSGKV 
       310        320        330        340        350
LVLQSQRTDF PYVSAAMPCF VIIIILCVPC CKKKTSAAEG PELVSLQVLD 
       360        370        380 
QHPVGTGDHR DAAQLGFQPL MSATGSTGST EGA
Length:383
Mass (Da):42,646
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4291DAA55583F9DA
GO
Isoform 21 Publication (identifier: Q29980-2) [UniParc]FASTAAdd to basket
Also known as: MICB21 Publication, ex3-del

The sequence of this isoform differs from the canonical sequence as follows:
     109-151: Missing.

Show »
Length:340
Mass (Da):37,651
Checksum:i3910DFA1B654C555
GO
Isoform 31 Publication (identifier: Q29980-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     24-41: EPHSLRYNLMVLSQDESV → VEMGFHRVSQDGLDLLTS
     42-383: Missing.

Note: A GC to AG nucleotide substitution in intron 1 generates a splice junction which gives rise to an additional exon between exons 1 and 2. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:41
Mass (Da):4,287
Checksum:iF092DA8237AFA871
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X6R344X6R344_HUMAN
MHC class I polypeptide-related seq...
MICB
383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JHB5A0A0G2JHB5_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JH58A0A0G2JH58_HUMAN
MHC class I polypeptide-related seq...
MICB
383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9D8A0A140T9D8_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9M6A0A140T9M6_HUMAN
MHC class I polypeptide-related seq...
MICB
383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JH91A0A0G2JH91_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T979A0A140T979_HUMAN
MHC class I polypeptide-related seq...
MICB
360Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9H4A0A140T9H4_HUMAN
MHC class I polypeptide-related seq...
MICB
317Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H7Q8F5H7Q8_HUMAN
MHC class I polypeptide-related seq...
MICB
351Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

The following alleles of MICB are known: MICB*001, MICB*002, MICB*003, MICB*004, MICB*005, MICB*006, MICB*007, MICB*008, MICB*009N, MICB*010, MICB*011, MICB*012, MICB*013, MICB*014, MICB*015, MICB*016, MICB*018, MICB*019, MICB*020, MICB*021N and MICB*022. MICB*009N and MICB*021N are null alleles which are not expressed. The sequence shown is that of MICB*001.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04406839E → G in allele MICB*002, allele MICB*003, allele MICB*004, allele MICB*005, allele MICB*006, allele MICB*007, allele MICB*008, allele MICB*010, allele MICB*011, allele MICB*012, allele MICB*013, allele MICB*014, allele MICB*015, allele MICB*016, allele MICB*018, allele MICB*019, allele MICB*020 and allele MICB*022. 2 PublicationsCorresponds to variant dbSNP:rs45578846Ensembl.1
Natural variantiVAR_04406968P → H in allele MICB*011. Corresponds to variant dbSNP:rs45583740Ensembl.1
Natural variantiVAR_04407075D → N in allele MICB*004 and allele MICB*020. Corresponds to variant dbSNP:rs3131639Ensembl.1
Natural variantiVAR_04407180K → E in allele MICB*002, allele MICB*007, allele MICB*008, allele MICB*014, allele MICB*015, allele MICB*016, allele MICB*019 and allele MICB*022. 2 PublicationsCorresponds to variant dbSNP:rs1065075Ensembl.1
Natural variantiVAR_04407288D → G in allele MICB*022. Corresponds to variant dbSNP:rs45486091Ensembl.1
Natural variantiVAR_044073105D → G in allele MICB*012. Corresponds to variant dbSNP:rs45502297Ensembl.1
Natural variantiVAR_044074121I → M in allele MICB*008. Corresponds to variant dbSNP:rs3134900Ensembl.1
Natural variantiVAR_059527136D → H. Corresponds to variant dbSNP:rs1051788Ensembl.1
Natural variantiVAR_044075136D → N in allele MICB*002, allele MICB*007, allele MICB*008, allele MICB*014, allele MICB*015, allele MICB*018, allele MICB*020 and allele MICB*022. 1 PublicationCorresponds to variant dbSNP:rs1051788Ensembl.1
Natural variantiVAR_044076212T → I in allele MICB*003. Corresponds to variant dbSNP:rs41293883Ensembl.1
Natural variantiVAR_044077215E → K in allele MICB*006 and allele MICB*015. Corresponds to variant dbSNP:rs45624537Ensembl.1
Natural variantiVAR_044078279R → K in allele MICB*007. Corresponds to variant dbSNP:rs45587032Ensembl.1
Natural variantiVAR_044079291G → S in allele MICB*013, allele MICB*014, allele MICB*015 and allele MICB*016. Corresponds to variant dbSNP:rs41273040Ensembl.1
Natural variantiVAR_044080300V → A in allele MICB*002, allele MICB*003, allele MICB*004, allele MICB*005, allele MICB*006, allele MICB*007, allele MICB*008, allele MICB*010, allele MICB*011, allele MICB*012, allele MICB*013, allele MICB*014 and allele MICB*015. 2 PublicationsCorresponds to variant dbSNP:rs45470602Ensembl.1
Natural variantiVAR_044081383A → T in allele MICB*003, allele MICB*004, allele MICB*010 and allele MICB*011. Corresponds to variant dbSNP:rs1065076Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05280124 – 41EPHSL…QDESV → VEMGFHRVSQDGLDLLTS in isoform 3. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_05280242 – 383Missing in isoform 3. 1 PublicationAdd BLAST342
Alternative sequenceiVSP_055246109 – 151Missing in isoform 2. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X91625 mRNA Translation: CAA62823.1
U65416 Genomic DNA Translation: AAB42011.1
AY885251 mRNA No translation available.
EF051579 Genomic DNA Translation: ABO16470.1
EF051580 Genomic DNA Translation: ABO16471.1
AK314228 mRNA Translation: BAG36899.1
BA000025 Genomic DNA Translation: BAB63307.1
AL662866 Genomic DNA No translation available.
AL663061 Genomic DNA No translation available.
BX001040 Genomic DNA No translation available.
BX005439 Genomic DNA No translation available.
CR753820 Genomic DNA No translation available.
CR753864 Genomic DNA No translation available.
CR788288 Genomic DNA No translation available.
BC044218 mRNA Translation: AAH44218.1
U69978 Genomic DNA Translation: AAB51802.1
U95729 mRNA Translation: AAB71642.1
U95730 mRNA Translation: AAB71643.1
U95731 mRNA Translation: AAB71644.1
U95732 mRNA Translation: AAB71645.1
U95733 mRNA Translation: AAB71646.1
U95734 mRNA Translation: AAB71647.1
AJ563706 Genomic DNA Translation: CAD91554.1
AF021221 mRNA Translation: AAC39846.1
AF021222 mRNA Translation: AAC39847.1
AF021223 mRNA Translation: AAC39848.1
AF021224 mRNA Translation: AAC39849.1
AF021225 mRNA Translation: AAC39850.1
AF021226 mRNA Translation: AAC39851.1
AB003609 Genomic DNA Translation: BAA23476.1
AB003610 Genomic DNA Translation: BAA23477.1
AB003611 Genomic DNA Translation: BAA23478.1
AB003612 Genomic DNA Translation: BAA23479.1
AB003613 Genomic DNA Translation: BAA23480.1
AB003614 Genomic DNA Translation: BAA23481.1
AB003615 Genomic DNA Translation: BAA23482.1
AB003616 Genomic DNA Translation: BAA23483.1
AB003617 Genomic DNA Translation: BAA23484.1
AJ251156, AJ251157 Genomic DNA Translation: CAB72101.1
AJ251158, AJ251159 Genomic DNA Translation: CAB72097.1
AJ251160, AJ251161 Genomic DNA Translation: CAB72098.1
AJ606906 Genomic DNA Translation: CAE54932.1
AJ606907 Genomic DNA Translation: CAE54933.1
AJ606908 Genomic DNA Translation: CAE54934.1
AJ606909 Genomic DNA Translation: CAE54935.1
AJ606910 Genomic DNA Translation: CAE54936.1
AJ606911 Genomic DNA Translation: CAE54937.1
AJ606912 Genomic DNA Translation: CAE54938.1
AJ606913 Genomic DNA Translation: CAE54939.1
AJ606914 Genomic DNA Translation: CAE54940.1
AJ606915 Genomic DNA Translation: CAE54941.1
AJ606916 Genomic DNA Translation: CAE54942.1
AJ606917 Genomic DNA Translation: CAE54943.1
AJ606918 Genomic DNA Translation: CAE54944.1
AJ606919 Genomic DNA Translation: CAE54945.1
AJ606920 Genomic DNA Translation: CAE54946.1
AJ606921 Genomic DNA Translation: CAE54947.1
AJ606922 Genomic DNA Translation: CAE54948.1
AJ606923 Genomic DNA Translation: CAE54949.1
AJ606929 Genomic DNA Translation: CAE54955.1
AJ606930 Genomic DNA Translation: CAE54956.1
AJ606931 Genomic DNA Translation: CAE54957.1

NCBI Reference Sequences

More...RefSeqi		NP_001276089.1, NM_001289160.1
NP_001276090.1, NM_001289161.1
NP_005922.2, NM_005931.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000399150; ENSP00000382103; ENSG00000204516
ENST00000427115; ENSP00000395391; ENSG00000204516
ENST00000428416; ENSP00000398412; ENSG00000206449
ENST00000436531; ENSP00000409414; ENSG00000238289
ENST00000436655; ENSP00000402484; ENSG00000238289
ENST00000438954; ENSP00000398212; ENSG00000234218
ENST00000443156; ENSP00000393355; ENSG00000227772
ENST00000546706; ENSP00000449672; ENSG00000231179
ENST00000551608; ENSP00000447696; ENSG00000224378

Database of genes from NCBI RefSeq genomes

More...GeneIDi		4277

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:4277

UCSC genome browser

More...UCSCi		uc003nto.6 human [Q29980-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91625 mRNA Translation: CAA62823.1
U65416 Genomic DNA Translation: AAB42011.1
AY885251 mRNA No translation available.
EF051579 Genomic DNA Translation: ABO16470.1
EF051580 Genomic DNA Translation: ABO16471.1
AK314228 mRNA Translation: BAG36899.1
BA000025 Genomic DNA Translation: BAB63307.1
AL662866 Genomic DNA No translation available.
AL663061 Genomic DNA No translation available.
BX001040 Genomic DNA No translation available.
BX005439 Genomic DNA No translation available.
CR753820 Genomic DNA No translation available.
CR753864 Genomic DNA No translation available.
CR788288 Genomic DNA No translation available.
BC044218 mRNA Translation: AAH44218.1
U69978 Genomic DNA Translation: AAB51802.1
U95729 mRNA Translation: AAB71642.1
U95730 mRNA Translation: AAB71643.1
U95731 mRNA Translation: AAB71644.1
U95732 mRNA Translation: AAB71645.1
U95733 mRNA Translation: AAB71646.1
U95734 mRNA Translation: AAB71647.1
AJ563706 Genomic DNA Translation: CAD91554.1
AF021221 mRNA Translation: AAC39846.1
AF021222 mRNA Translation: AAC39847.1
AF021223 mRNA Translation: AAC39848.1
AF021224 mRNA Translation: AAC39849.1
AF021225 mRNA Translation: AAC39850.1
AF021226 mRNA Translation: AAC39851.1
AB003609 Genomic DNA Translation: BAA23476.1
AB003610 Genomic DNA Translation: BAA23477.1
AB003611 Genomic DNA Translation: BAA23478.1
AB003612 Genomic DNA Translation: BAA23479.1
AB003613 Genomic DNA Translation: BAA23480.1
AB003614 Genomic DNA Translation: BAA23481.1
AB003615 Genomic DNA Translation: BAA23482.1
AB003616 Genomic DNA Translation: BAA23483.1
AB003617 Genomic DNA Translation: BAA23484.1
AJ251156, AJ251157 Genomic DNA Translation: CAB72101.1
AJ251158, AJ251159 Genomic DNA Translation: CAB72097.1
AJ251160, AJ251161 Genomic DNA Translation: CAB72098.1
AJ606906 Genomic DNA Translation: CAE54932.1
AJ606907 Genomic DNA Translation: CAE54933.1
AJ606908 Genomic DNA Translation: CAE54934.1
AJ606909 Genomic DNA Translation: CAE54935.1
AJ606910 Genomic DNA Translation: CAE54936.1
AJ606911 Genomic DNA Translation: CAE54937.1
AJ606912 Genomic DNA Translation: CAE54938.1
AJ606913 Genomic DNA Translation: CAE54939.1
AJ606914 Genomic DNA Translation: CAE54940.1
AJ606915 Genomic DNA Translation: CAE54941.1
AJ606916 Genomic DNA Translation: CAE54942.1
AJ606917 Genomic DNA Translation: CAE54943.1
AJ606918 Genomic DNA Translation: CAE54944.1
AJ606919 Genomic DNA Translation: CAE54945.1
AJ606920 Genomic DNA Translation: CAE54946.1
AJ606921 Genomic DNA Translation: CAE54947.1
AJ606922 Genomic DNA Translation: CAE54948.1
AJ606923 Genomic DNA Translation: CAE54949.1
AJ606929 Genomic DNA Translation: CAE54955.1
AJ606930 Genomic DNA Translation: CAE54956.1
AJ606931 Genomic DNA Translation: CAE54957.1
RefSeqiNP_001276089.1, NM_001289160.1
NP_001276090.1, NM_001289161.1
NP_005922.2, NM_005931.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JE6X-ray2.50A24-297[»]
2WY3X-ray1.80A/C24-341[»]
SMRiQ29980
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi110424, 45 interactors
CORUMiQ29980
STRINGi9606.ENSP00000252229

PTM databases

iPTMnetiQ29980
PhosphoSitePlusiQ29980
SwissPalmiQ29980

Polymorphism and mutation databases

BioMutaiMICB
DMDMi74706857

Proteomic databases

EPDiQ29980
jPOSTiQ29980
MassIVEiQ29980
MaxQBiQ29980
PaxDbiQ29980
PeptideAtlasiQ29980
PRIDEiQ29980
ProteomicsDBi3419
389
61282 [Q29980-1]
61283 [Q29980-3]
69573

Genome annotation databases

EnsembliENST00000399150; ENSP00000382103; ENSG00000204516
ENST00000427115; ENSP00000395391; ENSG00000204516
ENST00000428416; ENSP00000398412; ENSG00000206449
ENST00000436531; ENSP00000409414; ENSG00000238289
ENST00000436655; ENSP00000402484; ENSG00000238289
ENST00000438954; ENSP00000398212; ENSG00000234218
ENST00000443156; ENSP00000393355; ENSG00000227772
ENST00000546706; ENSP00000449672; ENSG00000231179
ENST00000551608; ENSP00000447696; ENSG00000224378
GeneIDi4277
KEGGihsa:4277
UCSCiuc003nto.6 human [Q29980-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		4277
DisGeNETi4277

GeneCards: human genes, protein and diseases

More...GeneCardsi		MICB
HGNCiHGNC:7091 MICB
HPAiHPA064618
MIMi180300 phenotype
602436 gene
neXtProtiNX_Q29980
PharmGKBiPA30812

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410J8TZ Eukaryota
ENOG41118IQ LUCA
HOGENOMiHOG000231246
InParanoidiQ29980
KOiK07985
OrthoDBi1276422at2759
PhylomeDBiQ29980
TreeFamiTF342166

Enzyme and pathway databases

ReactomeiR-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MICB human
EvolutionaryTraceiQ29980

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		4277
PharosiQ29980

Protein Ontology

More...PROi		PR:Q29980

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000204516 Expressed in 172 organ(s), highest expression level in blood
ExpressionAtlasiQ29980 baseline and differential
GenevisibleiQ29980 HS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMICB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q29980
Secondary accession number(s): A2AC57
, A6NP85, B0UZ10, B2RAK2, O14499, O14500, O19798, O19799, O19800, O19801, O19802, O19803, O78099, O78100, O78101, O78102, O78103, O78104, P79525, P79541, Q5GR31, Q5GR37, Q5GR41, Q5GR42, Q5GR43, Q5GR44, Q5GR46, Q5GR48, Q5RIY6, Q5SSK1, Q5ST25, Q7JK51, Q7YQ89, Q861E6, Q9MY18, Q9MY19, Q9MY20, Q9UBH4, Q9UBZ8, Q9UEJ0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 1, 1996
Last modified: November 13, 2019
This is version 158 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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