| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Enzyme |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.5.1.- |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.5.-.- |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/enzyme/2.-.-.- |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#subClassOf | http://purl.uniprot.org/core/Enzyme |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "The reaction occurs in four steps: NAD(+)-dependent dehydrogenation of spermidine (1a), formation of an enzyme-imine intermediate by transfer of the 4-aminobutylidene group from dehydrospermidine to the active site lysine residue (1b), transfer of the same 4-aminobutylidene group from the enzyme intermediate to the e1F5A precursor (1c), reduction of the e1F5A-imine intermediate to form a deoxyhypusine residue (1d)."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "For the plant enzyme, homospermidine can substitute for spermidine and putrescine can substitute for the lysine residue of the eIF5A precursor."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "Hence the overall reaction is transfer of a 4-aminobutyl group."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "The eukaryotic initiation factor eIF5A contains a hypusine residue that is essential for activity."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "Catalyzes the first reaction of hypusine formation from one specific lysine residue of the eIF5A precursor."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2000/01/rdf-schema#comment | "Hypusine is formed from deoxyhypusine by the action of EC 1.14.99.29."xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2004/02/skos/core#prefLabel | "deoxyhypusine synthase"xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10542236 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10611289 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/7592594 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/7673224 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10028184 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10734052 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2108161 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9188485 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9285092 |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2004/02/skos/core#altLabel | "spermidine dehydrogenase"xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2004/02/skos/core#altLabel | "(4-aminobutyl)lysine synthase"xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://www.w3.org/2004/02/skos/core#altLabel | "[eIF-5A]-deoxyhypusine synthase"xsd:string |
| http://purl.uniprot.org/enzyme/2.5.1.46 | http://purl.uniprot.org/core/replaces | http://purl.uniprot.org/enzyme/1.1.1.249 |