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http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Enzyme
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.1.3.-
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.1.-.-
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/enzyme/3.-.-.-
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#subClassOfhttp://purl.uniprot.org/core/Enzyme
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#comment"In humans, the enzyme is localized to late endosomal/lysosomal membranes."xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#comment"The enzyme from human is specific for PtdIns(4,5)P2 as substrate, as it cannot use PtdIns(3,4,5)P3, PtdIns(3,4)P2, PtdIns(3,5)P2, PtdIns5P, PtdIns4P or PtdIns3P."xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#comment"One is catalyzed by this enzyme and the other by EC 3.1.3.36, where the product is PtdIns4P."xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#comment"Two pathways exist in mammalian cells to degrade 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [PtdIns(4,5)P2]."xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2000/01/rdf-schema#comment"It can control nuclear levels of PtdIns5P and thereby control p53-dependent apoptosis."xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2004/02/skos/core#prefLabel"phosphatidylinositol-4,5-bisphosphate 4-phosphatase"xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12356723
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/16365287
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/17389247
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/17940011
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2004/02/skos/core#altLabel"PtdIns-4,5-P2 4-phosphatase"xsd:string
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/replaceshttp://purl.uniprot.org/enzyme/3.1.3.n3
http://purl.uniprot.org/enzyme/3.1.3.78http://purl.uniprot.org/core/activityhttp://purl.uniprot.org/enzyme/3.1.3.78#SIPA1D2D1DF6938FC31
http://purl.uniprot.org/enzyme/3.1.3.78http://www.w3.org/2004/02/skos/core#broaderTransitivehttp://purl.uniprot.org/enzyme/3.1.3.-
http://purl.uniprot.org/uniprot/A0A8D8V551http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78
http://purl.uniprot.org/uniprot/A0A1B6DL15http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78
http://purl.uniprot.org/uniprot/A0A914H297http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78
http://purl.uniprot.org/uniprot/A0AA47NZR4http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78
http://purl.uniprot.org/uniprot/A0AA39C5N9http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78
http://purl.uniprot.org/uniprot/A0A5E4CSK9http://purl.uniprot.org/core/enzymehttp://purl.uniprot.org/enzyme/3.1.3.78